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Men’s Health Self Injection Guide

At Skippack Pharmacy, we’re committed to supporting men’s health with personalized care and proven solutions. For men managing erectile dysfunction (ED), self-injection therapy can be a highly effective treatment. This guide covers what self-injection therapy is, how to use it, safety tips, and what to avoid; so you can regain confidence in your sexual health journey.

Products We Offer for Men’s Sexual Health

  • Sildenafil
  • Sildenafil RDT (Rapid Dissolve Tablet)
  • Tadalafil
  • Tadalafil RDT
  • Prostaglandin E1 (PGE)
  • Trimix
  • Quadmix

Oral medications like Sildenafil and Tadalafil are often first-line treatments. For those who don’t respond well to pills, injection therapies like PGE, Trimix, and Quadmix are highly effective alternatives.

What is Self-Injection Therapy?

Self-injection therapy involves using a very fine needle to inject medication directly into the side of the penis (corpus cavernosum). It enhances blood flow, resulting in a firm, natural-feeling erection within 5–20 minutes, regardless of arousal.

Why Choose Injection Therapy?
  • Fast and reliable results
  • Works even when oral medications don’t
  • No systemic side effects (like flushing or headaches

How to Use Self-Injection Therapy (Step-by-Step)

1. Gather Your Supplies
  • Your medication (PGE, Trimix, or Quadmix
  • Alcohol swab
  • Syringe (usually 0.5 mL insulin syringe)
  • Sharps container for disposal
2. Prepare the Medication
  • Wash your hands.
  • Use a clean, sterile syringe.
  • Draw the prescribed dose (usually between 0.05 mL – 0.3 mL depending on your doctor’s instructions).
  • Remove air bubbles by flicking the syringe and pushing the plunger slightly.
3. Choose an Injection Site
  • Inject into the side of the penis (10 o’clock or 2 o’clock position), avoiding veins.
  • Alternate sides with each injection to prevent scarring.
4. Administer the Injection
  • Wipe the site with an alcohol swab.
  • Hold the penis gently but firmly.
  • Insert the needle straight in (not at an angle) and inject slowly.
  • Withdraw the needle and apply light pressure with a cotton pad or swab for 1-2 minutes
5. Dispose of Materials Safely
  • Place needle in a sharps container.
  • Do not reuse needles or syringes.

Tips and Tricks for Best Results

When starting injection therapy, it’s important to start low and go slow. Begin with the lowest effective dose as prescribed by your healthcare provider. This allows your body to adjust and minimizes the risk of unwanted side effects. Try to stay relaxed during the process; taking a few deep breaths before injecting can help reduce anxiety and make the experience smoother. It’s also a good habit to track your doses in a logbook or app, noting the amount used, the results, and any side effects. This helps both you and your provider make informed adjustments if needed. Using a mirror can be a helpful trick, especially when first learning to locate veins and position the injection correctly. And to prevent irritation, bruising, or scarring, remember to rotate your injection sites. Never inject into the same spot repeatedly.

What to Watch Out For

  • Prolonged Erection (Priapism): Erections lasting more than 4 hours can be dangerous—seek immediate medical help.
  • Pain or Bruising: Some discomfort is normal. Severe pain may indicate improper injection or need for dose adjustment.
  • Curvature or Scarring (Peyronie’s Disease): Rotate injection sites to minimize risk.
  • Bleeding: A small drop is normal; persistent bleeding needs medical attention.
  • Infection: Redness, swelling, or warmth at the site are warning signs.

What NOT to Do

🚫 Don’t inject more than once in 24 hours.
🚫 Never mix medications unless instructed.
🚫 Do not inject into veins or top/bottom of the penis.
🚫 Don’t share your syringes or medications.
🚫 Never use old or expired medication.

Have Questions? We’re Here to Help.

At Skippack Pharmacy, your health and safety are our top priorities. We offer medication counseling, real-people responses, and ongoing support for your men’s health needs. Our pharmacists are experienced in injections and happy to guide you every step of the way.

📞 Contact us today to schedule a one-on-one consultation or refill your prescription.

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