- Men's Health
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by Skippack Pharmacy
Men’s Health Oral Medications: Sildenafil & Cialis
What You Should Know About These Trusted Treatments for Erectile Dysfunction
Erectile dysfunction (ED) is more common than many people think, and it’s nothing to be embarrassed about. At Skippack Pharmacy, we offer discreet, compassionate care and personalized treatment options to help men regain confidence and control. Two of the most well-known and effective oral medications for ED are Sildenafil (Viagra) and Tadalafil (Cialis). This guide will help you understand the key differences between them, how to take them, and how to get the best results—safely and confidently.
What Are Sildenafil and Tadalafil?
Both Sildenafil and Tadalafil are PDE5 inhibitors; medications that work by relaxing blood vessels and improving blood flow to the penis. They don’t increase sexual desire but help the body respond naturally to sexual stimulation. These medications are often a first-line treatment for ED and have helped millions of men worldwide.
What’s the Difference Between Them?
While both Sildenafil (Viagra) and Tadalafil (Cialis) are effective treatments for erectile dysfunction, they differ in how they’re used and how long they last.
Sildenafil typically takes effect within 30 to 60 minutes and lasts about 4 to 6 hours. It works best when taken on an empty stomach, as food, especially fatty meals, can delay its absorption. In contrast, Tadalafil also takes about 30 to 60 minutes to start working but can last up to 36 hours, earning it the nickname “the weekend pill.”
One of the biggest advantages of Tadalafil is its flexibility. It can be taken either as needed or once daily in a low-dose form, which allows for more spontaneous intimacy and is especially helpful for men who don’t want to plan around medication timing. Additionally, Tadalafil is less affected by food, making it a more convenient option for some users.
How and When to Take Oral ED Medications
Timing matters: Take Sildenafil or Tadalafil 30 to 60 minutes before sexual activity.
With or without food?: Sildenafil works best on an empty stomach, while Tadalafil can be taken with or without food.
Daily vs. as-needed: Tadalafil’s daily option allows for a constant, low level of medication in the system, which may benefit men who want more spontaneity or have both ED and BPH (enlarged prostate).
Tips and Tricks for Best Results
- Be patient: These meds don’t work instantly. Give it time—up to an hour.
- You still need stimulation: They help with blood flow, but sexual arousal is still necessary for them to work.
- Avoid heavy alcohol: Too much alcohol can make it harder to get or maintain an erection, even with medication.
- Plan ahead: Know your window of effectiveness. Sildenafil lasts about 4–6 hours, while Tadalafil can last up to 36.
- Don’t double dose: If the standard dose doesn’t work, talk to your provider. Don’t just increase on your own.
How Well Do They Work?
- Both medications are highly effective; up to 70–80% of men experience improved erections with either option. Results can vary based on health conditions, medications, and lifestyle factors. The key is to work with your provider or pharmacist to find the right dose and timing for your needs.
Side Effects to Be Aware Of
Most men tolerate these medications well, but side effects can occur. They’re typically mild and go away on their own.
Common Side Effects:
- Headache
- Facial flushing
- Stuffy or runny nose
- Upset stomach or indigestion
- Back pain or muscle aches (especially with Tadalafil)
- Dizziness or lightheadedness
Rare but Serious Side Effects:
- Vision or hearing changes
- Chest pain
- Erection lasting more than 4 hours (priapism—seek emergency care)
If you have heart conditions, are taking nitrates, or use alpha-blockers, it’s important to speak with your doctor before starting these medications.
Your Skippack Pharmacy Advantage
We know these conversations can feel awkward, but we’re here to make it easy and judgment-free. Whether you’re looking to try ED medications for the first time or want to switch to a more effective or convenient option, Skippack Pharmacy offers:
- Private consultations
- Competitive pricing
- Oral and injection medications
- Prescription refills and easy follow-ups
Call us today to speak with one of our trusted pharmacists or stop in for one-on-one counseling. We’ll help you choose the best medication, and plan to fit your needs and lifestyle.
